Nam Hyeong Kim, Hyejin Kwon, Zinah Hilal Khaleel, William F. DeGrado*, Yong Ho Kim*, and Yung Sam Kim* "Observation of reversible deformation of polymorphic IAPP oligomer in low temperature", The Journal of Physical Chemistry Letters (in preparation)
Nam Hyeong Kim, Hyejin Kwon, Juran Moon, Geun Young Jin, Deok Hyang Sa, Young Hyun No, Jiyoung Nam, Trung Thanh Thach, Jin Gyu Seol, Huong T. Kratochvil, Sayan Bagchi, William F. DeGrado*, Yong Ho Kim*, Yung Sam Kim*, "Channel-Water Dynamics are Correlated with the Conformational Changes of the M2 Viroporin Protein from Influenza A Virus", Chemical Science (in preparation)
Eun Sung Kang, Nam Hyeong Kim, Jaemin So, Hyunsub Ji, Hyeyeon Jeon, Taehwan Park, Young Hyun Noh, Jaecheol Lee*, Yong Ho Kim*, “PAM sequence independent CRISPR-Cas platform system for unrestricted genome editing”, TBD
Hayeon Bae, Hyunsub Ji, Yong Ho Kim," AI-driven nanoarchitectonics for targeted drug delivery"
Seongmin Ga, Songha Lee, Dongseon Shin, Wonhwa Lee*, Yong Ho Kim*, De novo design of Activin receptor type2B for treating sarcopenia, TBD
Woojung Jung, Suhyeon Kim, Jaewon Lee, Seongmin Ga, Je Moon Yoon, Minah Suh, Yong Ho Kim*, “Lipid nanoparticle-mediated dual mRNA therapy for localized and prolonged therapeutic effects in age-related macular degeneration”, TBD
Suhyeon Kim, Subin Lee, Hyeonggi Jeong, Songha Lee, Hyunsub Ji, Jaecheol Lee, Yong Ho Kim*, “De novo design of CAR/DAF binders for heart-targeted therapeutics”, TBD
Surim Soh, Eunsung Kang, Suhyeon Kim, Hyeyeon Jeon, Subin Lee, Sangseob Lee*, Yong Ho Kim*, "Structure-based engineering of newly discovered RsCas9 for enhanced enzymatic efficiency", TBD
Hyeonggi Jeong, Seongmin Ga, Woojung Jung, Yong Ho Kim*, Jaecheol Lee*, “Targeting LAMP2 deficiency in cardiomyocytes using LNP-mediated mRNA therapeutics for the treatment of Danon disease”, TBD
Hyunsub Ji, Eun Sung Kang, Nam Hyeong Kim, Songha Lee, Yong Ho Kim*, "Computational Design of Transferrin Receptor Binders for Brain Penetration", TBD
Sung Dong Kim, Hyunsub Ji, Yong Ho Kim, Mikyung Shin*, "injectable, adhesive, nicotinamide riboside-loaded chitosan hydrogel for recovery of myocardial infarction", TBD
Nam Hyeong Kim, Hyunsub Ji, DeGrado W.F.*, Yong Ho Kim "In silico phage display for protein binder facilitating brain penetration", TBD
Shengyang, Young Hyun Noh, Nam Hyeong Kim, Eun Sung Kang, Hyunsub Ji, Yong Ho Kim , Ho Seok Park"Anti-freezing, Ionic Conductive, Biocompatible Protein Hydrogel Electrolytes for Sustainable Aqueous Metal Batteries", TBD
Hayeon Bae, Hyeyeon Jeon, Eun Sung Kang, Yong Ho Kim "Optimized CasΦ Protein Engineering for Efficient Ocular Delivery"
Subin Lee, Do Hyun Bae, Dongsun Shin, Seongmin Ga, Yong Ho Kim*, "De Novo design of type specific amyloid-β probe for early diagnosis of Alzheimer’s disease with optical retina imaging", TBD
Design1 "AI-driven protein design for TfR": Hyunsub Ji, Eun Sung Kang, Dong Sun Shin, Nam Hyeong Kim, Yong Ho Kim (아임뉴런 공동연구)
Design2 "AI-driven protein design of viral drug for targeting spike protein and other glyco-proteins": Hyunsub Ji, Songha Lee, Eun Sung Kang, Dong Sun Shin, Hyeyeon Jeon, Yong Ho Kim (생명공학연구원, 아임뉴런 공동연구)
Design3 "De novo protein design for targeted binding of diverse backbone in all narcotics": Hyunsub Ji, Songha Lee, Dong Sun Shin, Yong Ho Kim
Design4 "De novo protein design for chiral selection in small molecules": Songha Lee, Hyunsub Ji, Dong Sun Shin, Yong Ho Kim
Design5 “Computational design of a photoswitchable Ca2+ indicator for in vivo calcium imaging in skeletal muscle”: Do Hyun Bae, Zinah H. Khaleel, Jae Kyoung Lee, Nam Hyeong Kim, Yong Ho Kim (Prof. William F. DeGrado, 이원화 교수, 서민아 교수, 김성기 교수 공동연구)
Design6 "Anti-parallel hetero-dimer coiled-coil as protein complex engagement": Woojung Jung, Do Hyun Bae, Yong Ho Kim
Design7 "De novo design of type specific amyloid-β probe for diagnosis of Alzheimer’s disease": Dong Sun Shin, Hyeyeon Jeon, Do Hyun Bae, Seongmin Ga, Suhyeon Kim, Yong Ho Kim (서민아 교수 공동연구)
Design8 “Design of Myostatin Antagonist for increasing muscle treating sarcopenia”: Seongmin Ga, Songha Lee, Dong Sun Shin, Subin Lee, Suhyeon Kim, Hayeon Bae, Yongbin Cho, Yong Ho Kim (동성, 이원화 교수 공동연구)
Design9 “Structure-based de novo design of adiponectin receptor agonists for muscle regeneration”: Songha Lee, Subin Lee , Suhyeon Kim, Seongmin Ga, Hayeon Bae, Yong Ho Kim (동성, 이재철 교수 공동연구)
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Cas1 "Independent PAM specificity": Eun Sung Kang, Nam Hyeong Kim, Hyeyeon Jeon, Taehwan Park, Hyunsub Ji, Ik Jung Kim, Sion Park, Young Hyun Noh, Yong Ho Kim(아임뉴런, 이재철 교수, 서민아 교수 공동연구)
Cas2 "New discovery of mini-Cas proteins": Eun Sung Kang, Hyeyeon Jeon, Taehwan Park, Nam Hyeong Kim, Yong Ho Kim (이상섭 교수, 이재철 교수, 아임뉴런 공동연구)
Cas3 "Structural-based redesign of RsCas9": Suhyeon Kim, Hyeyeon Jeon, Subin Lee, Eun Sung Kang, Nam Hyeong Kim, Yong Ho Kim (이상섭 교수, 허준호 교수, 아임뉴런 공동연구)
Cas4 "Transposase": Hyeyeon Jeon, Eun Sung Kang, Young Je Kim, Yong Ho Kim (이상섭 교수 공동연구)
Cas5 "Efficient intracellular delivery of genetic editor with cell penetrating peptide-Cas Phi conjugate)": Hyeyeon Jeon, Hayeon Bae, Eun Sung Kang, Young Hyun Noh, Yong Ho Kim(서민아 교수 공동연구)
Cas6 “PAM binding motif(PBM) design for unrestricted gene editing protein within PI domain”: Young Je Kim, Eun Sung Kang, Hyunsub Ji, Yong Ho Kim
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RNA1 “Computational protein design-based heart-targeted mRNA therapeutics for the protein replacement therapy of Danon disease”: Suhyeon Kim, Seongmin Ga, Subin Lee, Woojung Jung, Yong Ho Kim (이재철 교수, 삼성서울병원 공동연구)
RNA2 “Lipid nanoparticle-mediated dual mRNA therapy for localized and prolonged therapeutic effects in age-related macular degeneration”: Woojung Jung, Suhyeon Kim, Seongmin Ga, Yong Ho Kim (삼성서울병원, 서민아 교수 공동연구)
RNA3 “BBB-peneratable lipid nanoparticle mediated mRNA therapeutics for the treatment of neurodegenerative diseases”: Seongmin Ga, Hyunsub Ji, Suhyeon Kim, Woojung Jung, Subin Lee, Yongbin Cho, Yun Jeong Cha, Yong Ho Kim* (아임뉴런, 이재철 교수, 서민아 교수 공동연구)
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Sensor1 "Designed protein based narcotic sensor": Hyunsub Ji, Song ha Lee, Dong Sun Shin, Yong Ho Kim, Oh Seok Kwon (권오석 교수 공동연구)
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Biomaterial1 “Transcellular peptide-drug conjugate (PDC) as an effective androgen receptor antagonist for androgenic alopecia”: Do Hyun Bae, Hayeon Bae, Yong Ho Kim (이재철 교수, 서민아 교수 공동연구)
Biomaterial2 "Supramolecular self-assembly of protein copolymer utilizing coiled-coil protein to end-block": Young Hyun No, Woojung Jung, Do Hyun Bae, Yong Ho Kim (애리조나 대학 김민규 교수 공동연구)
Biomaterial3 "scFv Coiled-Coil Protein Complex": Young Hyun No, Cho Yeon Lee, Dong Ho Kim, Sang Ho Lee, Kun Nyun Kim, Yong Ho Kim (윤완수 교수 공동연구)
Biomaterial4 “Homology-based design of EGF-like peptides for skin regeneration and its application as a nanofiber patch” : Suhyeon Kim, Hayeon Bae, Seongmin Ga, Songha Lee, Subin Lee, Yongbin Cho, Yong Ho Kim (동성, 안성필 교수, 이재철 교수 공동연구)
Biomaterial5 “Antimicrobial peptide-based nanofiber patch for the treatment of inflammatory skin diseases”: Suhyeon Kim, Hayeon Bae, Seongmin Ga, Songha Lee, Yong Ho Kim (제네웰, 안성필 교수 공동연구)